Co~(2+)/Dy~(3+)掺杂纳米立方Fe_3O_4的热还原制备及磁靶向滞留性能

采用热还原沉淀法制备了一系列Co~(2+)/Dy~(3+)掺杂的纳米立方MxFe3-xO4磁性颗粒.利用X射线衍射仪、透射电子显微镜和振动样品磁强计研究了不同含量掺杂离子对MxFe3-xO4晶体结构、形貌及磁性的影响.研究发现,掺杂未改变母体的对称性,但母体形貌逐渐从立方体向球体过渡;Co~(2+)和Dy~(3+)的掺杂对于铁氧体磁学性质的影响明显不同,当Co~(2+)实际掺杂量为0.44和Dy~(3+)实际掺杂量为0.05时,MxFe3-xO4立方磁性粒子的饱和磁化强度(Ms)达到最大值,分别为76.65和70.21 A·m2·kg-1.与超顺磁性Fe_3O_4球体相比,高磁性掺杂Fe_3O_4立方体在体外模拟磁流体磁靶向定位实验中显示出较高的滞留率.

Thermal Reduation Preparation of Co2+/Dy3+Doped Cubic Fe3O4 and Their Magnetic Targeting Retention

Co2+/Dy3+ doped Fe3O4 nanoparticles(MxFe3-xO4) were synthesized by the thermal reduction and co-precipitation methods . The structure, morphology and magnetic properties of Mx Fe3-x O4 were characterized by means of X-ray diffractometer ( XRD ) , transmission electron microscope ( TEM ) and vibrating sample magnetometer(VSM). The results show that the dopants did not change the maternal symmetry, and the mater-nal morphology gradually transformed from cube to sphere. The Mx Fe3-x O4 cubic magnetic particles have maxi-mum saturation magnetization of 7665 and 7021 A · m2 · kg-1 , respectively, when Co2+ actual doping amount is equal to 044 and Dy3+actual doping amount is equal to 005 Compared with the superparamagnet-ic Fe3 O4 , the cubic high magnetic doped Fe3 O4 nanoparticles showed a high retention rate in the simulated magnetic fluid magnetic targeting experiment in vitro.