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One-Pot Synthesis of Dihydropyrimidinones/Thiones Catalyzed by White Marble a Metamorphic Rock: an Efficient and Reusable Catalyst for the Biginelli Reaction
Authors:K El Mejdoubi  B Sallek  H Cherkaoui  H Chaair  H Oudadesse
Institution:1.Laboratory of Agroressources, Polymers and Process Engineering, Faculty of Sciences,Ibn Tofa?l University,Kenitra,Morocco;2.Laboratory of Processes Engineering,Faculty of Science and Techniques Mohammedia,Mohammedia,Morocco;3.Institute of Chemical Sciences of Rennes UMR CNRS 6226,University of Rennes, 1,Rennes,France
Abstract:In this work, we report a simple, efficient and green protocol for the synthesis of dihydropyrimidinones/thiones (products of Biginelli reaction) by the use of white marble as an effective heterogeneous catalyst. Short reaction times, high product yields, simple processing procedure and reusability of the catalyst are the superior characteristics of this protocol.
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