1. Division of Cell Signalling & Immunology, College of Life Sciences, University of Dundee, Dundee, DD1 5EH, Scotland, UK
Abstract:
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Highlights? AMP-activated protein kinase (AMPK) is a sensor of cellular energy status ? Drugs that activate AMPK have potential in type 2 diabetes and in cancer ? Many existing drugs and xenobiotics (e.g., metformin, salicylate) activate AMPK ? Most, but not all, AMPK-activating xenobiotics inhibit mitochondrial function
