Synthesis and transformation of N-oxides of some imidazo[4,5-b]pyrazine derivatives |
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Authors: | A. S. Elina I. S. Musatova |
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Affiliation: | (1) S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry Institute, Moscow |
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Abstract: | The Böckelheide reaction was accomplished with a number of imidazo[4,5-b]pyrazine N-oxides, and the N-oxidation of the resulting acetoxy(hydroxy)methyl derivatives of imidazo[4,5-b]pyrazine and 6-bromo-1-methylimidazo[4,5-b]pyrazine was studied. The hydrolytic cleavage of 6-bromo-1-methylimidazo[4,5-b]pyrazine and its 4-N-oxide was studied.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 690–693, May, 1975. |
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