Selective enzymatic reduction of aldehydes |
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Authors: | Sello Guido Orsini Fulvia Bernasconi Silvana Di Gennaro Patrizia |
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Affiliation: | Dipartimento di Chimica Organica e Industriale, Università degli Studi di Milano, via Venezian 21, 20133 Milano, Italy. guido.sello@unimi.it |
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Abstract: | Highly selective enzymatic reductions of aldehydes to the corresponding alcohols was performed using an E. coli JM109 whole cell biocatalyst. A selective enzymatic method for the reduction of aldehydes could provide an eco-compatible alternative to chemical methods. The simplicity, fairly wide scope and the very high observed chemoselectivity of this approach are its most unique features. |
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