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Fabrication of a Nanostructure Based Electrochemical Sensor for Voltammetric Determination of Epinephrine,Uric Acid and Folic Acid
Authors:Hadi Mahmoudi Moghaddam  Hadi Beitollahi  Somayeh Tajik  Hossein Soltani
Affiliation:1. Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran;2. Environmental Health Engineering Research Center and Department of Environmental Health, School of Public Health, Kerman University of Medical Sciences, Kerman, Iran;3. Environment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran;4. Department of Chemistry, Shahid Bahonar University of Kerman, P.O. Box 76175–133, Kerman, Iran, Phone No: 00983426226613, Fax No: 00983426226617
Abstract:
A carbon paste electrode (CPE) was modified by incorporation of graphene nano sheets and a ferrocene derivative. The modified electrode showed an excellent electrocatalytic effect on the oxidation of epinephrine. In phosphate buffer solution (PBS) of pH 7.0, the oxidation current increased linearly with concentration of epinephrine in the range of 0.05–550.0 µM and a detection limit (3σ) 27.0 nM was obtained for epinephrine. Then the modified electrode was used to determine epinephrine in an excess of uric acid and folic acid by SWV.
Keywords:Epinephrine  Uric Acid  Folic Acid  Simultaneous determination  Graphene Nanosheets
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