| 市售虾中磺胺甲噁唑的LC-MS-MS定量分析 |
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| 引用本文： | 赵贵平,蒋宏键.市售虾中磺胺甲噁唑的LC-MS-MS定量分析[J].分析测试学报,2004,23(Z1):237-239. |
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| 作者姓名： | 赵贵平 蒋宏键 |
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| 作者单位： | 沃特斯中国有限公司,北京,100027 |
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| 摘 要： | 当前各国对食品安全都极为重视,我国以及发达国家相继制定了相关兽药用量的法规和标准,尽管中国已经加入到了WTO,但我国的畜禽产品出口还是遇到了很多困难,农药、兽药、饲料添加剂等非法滥用,造成药物残留而直接影响到人类的健康。如引发癌症,婴儿畸形,代谢紊乱以及抗药性等诸多问题。其中磺胺类兽药是一类受到严格限制使用的兽药,本文研究了市售虾中磺胺甲(口恶)唑定量分析方法,检出限绝对量可达到0.5pg,完全满足发达国家的最低检出规定的苛刻标准。
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A Quantitative Analysis of Sulfamethoxazole in Shrimps by LC-MS-MS |
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| ZHAO Gui-ping,JIANG Hong-jian.A Quantitative Analysis of Sulfamethoxazole in Shrimps by LC-MS-MS[J].Journal of Instrumental Analysis,2004,23(Z1):237-239. |
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| Authors: | ZHAO Gui-ping JIANG Hong-jian |
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| Abstract: | A sensitive LC - MS - MS method for the quantitation of sulfamethoxazole in shrimps using HPLC MS - MS system was developed in this study. The Limit of quantitation(LOQ) of sulfamethoxazole was 1 pg(LOD) for sulfamethoxazol in shrimps was in the low ng/mL level(0.05 ng/mL, S//VRMS= 25) . Linearity was demonstrated over the 0.1 - 100 ng/mL range with an excellent linear correlation coefficient of 0.999 91. |
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| Keywords: | HPLC-MS-MS Sulfamethoxazole |
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