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| Interactions between DNA and histones－ a dynamic process of nucleosome formation | |
| 作者姓名： | 李伟 王鹏业 窦硕星 童培庆 |
| 作者单位： | (1)Department of Physics, Nanjing Normal University, Nanjing 210097, China; (2)Laboratory of Soft Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100080, China; (3)Laboratory of Soft Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100080, China; Department of Physics, Nanjing Normal University, Nanjing 210097, China |
| 基金项目： | Project supported by the National Natural Science Foundation of China (Grant No 60025516). |
| 摘 要： | We have studied the dynamic process of interactions between a DNA chain and a histone octamer by numerical simulations.It is found that DNA indeed may wrap around the histone octamer about two turns as in the actual situations.The simulation shows that the interaction potential between DNA and histone is a key factor for the wrapping of DNA,and the temperature is also an important parameter in the process. |
| 关 键 词： | DNA 组蛋白 相互作用 动力过程 |
| 收稿时间： | 2002-09-13 |
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