Acylated flavonoid glycosides from Barringtonia racemosa |
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Authors: | Quach Thi Thanh Van Le Thi Vien Tran Thi Hong Hanh Phan Thi Thanh Huong Nguyen The Cuong Nguyen Phuong Thao |
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Institution: | 1. Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam;2. Graduate University of Science and Technology, VAST, Hanoi, Vietnam;3. Institute of Ecology and Biological Resources, VAST, Hanoi, Vietnam |
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Abstract: | AbstractUsing various chromatographic separations, three new acylated flavonoid glycosides, namely barringosides G–I (1–3), were isolated from the water-soluble extract of Barringtonia racemosa branches and leaves. The structure elucidation was performed by extensive analysis of the 1D and 2D NMR and HR-QTOF-MS data. Of the isolated compounds, barringoside I (3) showed moderate inhibitory effects on LPS-induced NO production in RAW264.7 cells with an IC50 of 52.48?±?1.04?µM. |
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Keywords: | Barringtonia racemosa Lecythidaceae flavonoid glycoside NO production |
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