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Acylated flavonoid glycosides from Barringtonia racemosa
Authors:Quach Thi Thanh Van  Le Thi Vien  Tran Thi Hong Hanh  Phan Thi Thanh Huong  Nguyen The Cuong  Nguyen Phuong Thao
Institution:1. Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam;2. Graduate University of Science and Technology, VAST, Hanoi, Vietnam;3. Institute of Ecology and Biological Resources, VAST, Hanoi, Vietnam
Abstract:Abstract

Using various chromatographic separations, three new acylated flavonoid glycosides, namely barringosides G–I (13), were isolated from the water-soluble extract of Barringtonia racemosa branches and leaves. The structure elucidation was performed by extensive analysis of the 1D and 2D NMR and HR-QTOF-MS data. Of the isolated compounds, barringoside I (3) showed moderate inhibitory effects on LPS-induced NO production in RAW264.7 cells with an IC50 of 52.48?±?1.04?µM.
Keywords:Barringtonia racemosa  Lecythidaceae  flavonoid glycoside  NO production
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