Chloromethylstyrene encapsulated and quaternized silica anion exchanger in high performance liquid chromatography

A kind of strong anion exchanger (SAX) was prepared with chloromethylstyrene encapsulated silica. This strong anion silica column has superior ability for the separation of anions, organic acids and also the mixture of them. Using this strong anion exchanger, the sulfonic acids can be separated. With gradient elution, the separation of petroleum mono- and di- sulfonates in Yumen sample can be also well obtained. This anion exchanger’s stability has been studied. After continuous use for three months the carbon and nitrogen contents and the chromatographic behavior of the exchanger were unchanged.