| 流动注射-化学发光法测定乌拉地尔 |
| |
| 引用本文： | 郎惠云,李亚荣,张维平,张秀军,申晔华. 流动注射-化学发光法测定乌拉地尔[J]. 高等学校化学学报, 2003, 24(4): 618-620 |
| |
| 作者姓名： | 郎惠云 李亚荣 张维平 张秀军 申晔华 |
| |
| 作者单位： | 西北大学化学系,西安,710069;西北大学化学系,西安,710069;西北大学化学系,西安,710069;西北大学化学系,西安,710069;西北大学化学系,西安,710069 |
| |
| 基金项目： | 陕西省自然科学基金 (批准号 :0 1JK0 73)资助 |
| |
| 摘 要： | 乌拉地尔 (Urapidil)即 6 - { [3 - [4- (o-甲氧苯基 ) - 1 -哌嗪 ]-丙基 ]-氨基 } - 1 ,3 -二甲基脲嘧啶 ,又名乌Scheme 1 The chemical structure of Urapidil拉尔碱或压宁定 ,为苯哌嗪取代的脲嘧啶衍生物 ,其结构见 Scheme 1 .乌拉地尔是一种高选择性的α受体阻滞剂 ,能使
|
| 关 键 词： | 流动注射 化学发光 乌拉地尔 |
| 文章编号： | 0251-0790(2003)04-0618-03 |
| 收稿时间： | 2002-05-29 |
Determination of Urapidil by Flow Injection Chemiluminescence |
| |
| LANG Hui Yun ,LI Ya Rong,ZHANG Wei Ping,ZHANG Xiu Jun,SHEN Yie Hua. Determination of Urapidil by Flow Injection Chemiluminescence[J]. Chemical Research In Chinese Universities, 2003, 24(4): 618-620 |
| |
| Authors: | LANG Hui Yun LI Ya Rong ZHANG Wei Ping ZHANG Xiu Jun SHEN Yie Hua |
| |
| Affiliation: | Department of Chemistry, Northwest University, Xi′an 710069, China |
| |
| Abstract: | A reverse flow injection chemiluminescence(CL) method for the determination of urapidil was firstly described. It was found that the CL intensity from the Luminol ClO- system could be enhanced in the presence of urapidil. The increase of CL emission was correlated with urapidil mass concentration in the range from 0.2 to 100 μg/mL, the detection limit was 0.01 μg/mL and the relative standard deviation was 1.3%(ρ =4 μg/mL, n =11), a sampling frequency of 150 h-1 was attained. The method was applied to the determination of leucoge in pharmaceutical preparations with recovery of 101.0% and 101.3%. |
| |
| Keywords: | Flow injection Chemiluminescence Urapidil |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《高等学校化学学报》浏览原始摘要信息 |
|
点击此处可从《高等学校化学学报》下载全文 |
|
