Preparation and adsorption properties of phospho‐L‐glutamic acid on hydroxyapatite

Phospho‐L‐glutamic acid was successfully prepared by the phosphorylation of glutamic acid, and its adsorption on synthetic hydroxyapatite (HAP) was studied together with glutamic. The adsorption behaviors of both adsorbates were adequately described by a Langmuirian model. From the comparison between two different adsorbates, the results of the investigation indicated that the phosphate group in phospho‐L‐glutamic acid can greatly enhanced the adsorption affinity for HAP, the improvement of which was achieved through replacing the same group on the surface of HAP and interacting with the surface calcium ion of HAP by electrostatic attraction. The results obtained laid the solid foundation for further research on the regulating function of phosphorylated amino acids with hydroxyapatite biological composites. Copyright © 2010 John Wiley & Sons, Ltd.