Toward standardization of quality assessment in laboratory medicine by using the same matrix samples for both internal and external quality assessments |
| |
Authors: | Ibrahim Unsal Abdurrahman Coskun Mustafa Serteser Tamer C Inal Aysel Ozpinar |
| |
Institution: | (1) School of Medicine, Department of Biochemistry, Acibadem University, Gulsuyu, Maltepe, Istanbul, Turkey; |
| |
Abstract: | The main purpose of quality assurance procedures in clinical laboratories is to ensure that test results are appropriate to
maintain excellence in the diagnosis, monitoring, and treatment of disease. However, in current practice, no standardized
procedure or frequency for the evaluation of methods exists, particularly in external quality assessment. Furthermore, different
quality control materials are typically used for internal and external quality assessment. To overcome these discrepancies,
we used samples with the same matrix for both internal and external quality assessments of a group test performed in our laboratory.
We then calculated total error using real bias (target value obtained by reference method) and the imprecision of each test
and compared our results with the total error allowable, derived from biological variation data. We suggest that the strategy
of using the same matrix samples for both internal and external quality assessment is cost-effective, can be readily used
by staff, and will facilitate the standardization of quality control in clinical laboratories. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|