Chemical Constituents from the Hulls of <Emphasis Type="Italic">Oryza sativa</Emphasis> with Cytotoxic Activity |
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Authors: | I M Chung M Ali S J Hahn N A Siddiqui Y H Lim A Ahmad |
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Institution: | (1) Department of Applied Life Science, Konkuk University, Seoul, 143-701, South Korea;(2) Faculty of Pharmacy, Hamdard University, New Delhi, 110062, India;(3) Department of Pharmacy, I. E. T., M. J. P. Rohilkhand University, Bareilly, 243006, India;(4) Department of Molecular Biotechnology, Bio/Molecular Informatics Center, Konkuk University, Seoul, 143-701, Korea |
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Abstract: | Five new compounds, orizaterpenol (1), orizaterpenoid (2), orizaterpenyl benzoate (3), orizanor-diterpenyl benzoate (4), and orizaditerpenyl benzoate (5), along with nine known compounds, were isolated and identified from the rice hulls of Oryza sativa. Their structures were elucidated with the help of different spectroscopic techniques. Orizaterpenol (1) and the known momilactone A (6) and B (7) were found to have cytotoxic effects against P388 murine leukaemia cells, while the other new and known compounds exhibited weak cytotoxicity.__________Published in Khimiya Prirodnykh Soedinenii, No. 2, pp. 146–151, March–April, 2005. |
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Keywords: | Oryza sativa L Poaceae rice hull composition orizaterpenol orizaterpenoid orizaterpenyl benzoate orizanor-diterpenyl benzoate orizaditerpenyl benzoate |
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