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Self-Assembly of a Tetrahedral Lectin into Predesigned Diamondlike Protein Crystals
Authors:Nir Dotan  Dorit Arad  Felix Frolow  Amihay Freeman
Abstract:
Binding sites analogous to those of sp 3 carbon are presented by concanavalin A. This lectin has now been cross-linked with a bismannopyranoside which contains the C2 spacer required to form the computer-modeled diamondlike three-dimensional protein lattice shown in the picture.
Keywords:Crystal engineering  Lectins  Molecular modeling  Proteins  Supramolecular chemistry
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