Direct ortho-arylation of 2-arylbenzoxazoles via C-H activation |
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| Authors: | Fan Yang Zhiwu Zhu Junli Zhang Yanan Li |
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| Affiliation: | Department of Chemistry, Key Laboratory of Chemical Biology and Organic Chemistry of Henan Province, Key Laboratory of Applied Chemistry of Henan Universities, Zhengzhou University, Zhengzhou 450052, PR China |
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| Abstract: | ![]()
A new and highly regioselective arylation of 2-arylbenzoxazoles based on C-H activation has been developed. The results represent the first examples of palladium-catalyzed direct ortho-arylation of 2-arylbenzoxazoles and also provide a facile route for the synthesis of complicated structures containing arylated benzoxazoles moieties. |
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| Keywords: | Arylation C-C coupling Palladium catalysis C-H activation |
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