Synthesis of new arylidene derivatives of 3-aminorhodanine

The synthesis of new arylidene derivatives of 3 -aminorhodanine has been effected. It has been established that the condensation of 3-aminorhodanine with aldehydes in an alcoholic medium gives 3′-arylidene derivatives. Similar reactions in an ammoniacal medium lead to 5-derivatives of 3-aminorhodanine. 3′, 5-Diarylidene derivatives can be obtained by condensing 3′-aminorhodanine with an excess of an aldehyde in glacial acetic acid, except for the salicylidene and 9-anthrylidene derivatives, the synthesis of which can be carried out only in two stages.