Efficient syntheses of imidazolo[1,2-a]pyridines and -[2, 1-a]isoquinolines |
| |
| Authors: | Katritzky A R Qiu G Long Q H He H Y Steel P J |
| |
| Institution: | Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200, USA. katritzky@chem.ufl.edu |
| |
| Abstract: | 2-Aminopyridines 1a-c and 1-aminoisoquinoline with 1-chloromethylbenzotriazole give 2-amino-1-alpha-benzotriazol-1-ylmethyl]pyridinium chlorides 2a-c and 1-amino-2-(alpha-benzotriazol-1-ylmethyl)isoquinolinium++ + chloride 12, respectively. Compounds 2a-c and 12 react with aryl aldehydes 3a-h to afford imidazolo1,2-a]pyridines 7a-k and imidazolo2, 1-a]isoquinolines 13a,b in good yields. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
