| Synthesis and Crystal Structure of Metronidazole-derived Compound |
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| 作者姓名： | 曹平 方瑞琴 李环球 朱海亮 |
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| 作者单位： | Institute of Functional Biomolecules State Key Laboratory of Pharmaceutical Biotechnology，Nanjing University，Institute of Functional Biomolecules，State Key Laboratory of Pharmaceutical Biotechnology，Nanjing University，Institute of Functional Biomolecules，State Key Laboratory of Pharmaceutical Biotechnology，Nanjing University，Institute of Functional Biomolecules，State Key Laboratory of Pharmaceutical Biotechnology，Nanjing University，Nanjing 210093，China，Nanjing 210093，China，Nanjing 210093，China，Nanjing 210093，China |
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| 摘 要： | A MET-OH derivative,MET-OTs 1,was designed,prepared and structurally charac-terized by single-crystal X-ray diffraction. X-ray structure analysis reveals that 1 crystallizes in the monoclinic system,space group P21/c,with a=16.1178(14),b=7.5473(6),c=13.4161(11),V= 1520.3(2)3,β=111.3210(10)o,Z=4,Dc=1.421 g/cm3 and F(000)=680.
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| 关 键 词： | 甲硝哒唑 晶体结构 氯化物 4-甲基-苯磺酰胺 |
| 收稿时间： | 2007-01-18 |
| 修稿时间： | 2007-02-18 |
Synthesis and Crystal Structure of Metronidazole-derived Compound |
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| CAO Ping,FANG Rui-Qin,LI Huan-Qiu,ZHU Hai-Liang.Synthesis and Crystal Structure of Metronidazole-derived Compound[J].Chinese Journal of Structural Chemistry,2007,26(11):1322-1326. |
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| Authors: | CAO Ping FANG Rui-Qin LI Huan-Qiu ZHU Hai-Liang |
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| Abstract: | A MET-OH derivative, MET-OTs 1, was designed, prepared and structurally charac- terized by single-crystal X-ray diffraction. X-ray structure analysis reveals that 1 crystallizes in the monoclinic system, space group P21/c, with a = 16.1178(14), b = 7.5473(6), c = 13.4161(11) (A), V = 1520.3(2) (A)3, β = 111.3210(10)o, Z = 4, Dc = 1.421 g/cm3 and F(000) = 680. |
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| Keywords: | metronidazole (MET-OH) crystal structure 4-methyl-benzenesufonyl chloride Compound Crystal Structure space group structure analysis monoclinic system diffraction derivative |
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