Nickel‐Catalyzed Amination of Aryl Chlorides with Ammonia or Ammonium Salts |
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| Authors: | Rebecca A. Green Prof. John F. Hartwig |
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| Affiliation: | Department of Chemistry, University of California, Berkeley, Berkeley, California 94720 (USA) |
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| Abstract: | ![]()
The nickel‐catalyzed amination of aryl chlorides to form primary arylamines occurs with ammonia or ammonium sulfate and a well‐defined single‐component nickel(0) precatalyst containing a Josiphos ligand and an η2‐bound benzonitrile ligand. This system also catalyzes the coupling of aryl chlorides with gaseous amines in the form of their hydrochloride salts. |
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| Keywords: | amination ammonia arylation cross‐coupling nickel |
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