Regioselective synthesis of 1-alkyl-5-(indol-3-yl- and -2-yl)pyrrolidin-2-ones from available reagents |
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| Authors: | A. V. Sadovoy A. E. Kovrov G. A. Golubeva L. A. Sviridova |
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| Affiliation: | (1) M. V. Lomonosov State University, Moscow, 119992, Russia |
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| Abstract: | ![]()
The reaction under mild conditions of 1-alkyl-5-hydroxypyrrolidin-2-ones with different indoles having a free 3 position leads exclusively to 1-alkyl-5-(indol-3-yl)pyrrolidin-2-ones but if position 3 is occupied to 1-alkyl-5-(indol-2-yl)pyrrolidin-2-ones. |
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