Samarium-promoted coupling of pyridine-based heteroaryl analogues of benzylic acetates with carbonyl compounds |
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| Authors: | Weitgenant Jeremy A Mortison Jonathan D Helquist Paul |
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| Institution: | Department of Chemistry and Biochemistry and Walther Cancer Research Center, 251 Nieuwland Science Hall, University of Notre Dame, Notre Dame, IN 46556, USA. |
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| Abstract: | 2-Substituted pyridine, quinoline, isoquinoline, bipyridine, and 1,10-phenanthroline analogues of benzylic acetates undergo SmI(2)-promoted coupling with aldehydes and ketones to afford (2-hydroxyalkyl)heteroaromatics. reaction: see text] |
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