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Electrospinning of the hydrophilic poly (2-hydroxyethyl methacrylate) and its copolymers with 2-ethoxyethyl methacrylate
Authors:Martin Přádný  Lenka Martinová  Jiří Michálek  Tat’ána Fenclová  Eva Krumbholcová
Affiliation:(1) Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, 162 06 Prague 6, Czech Republic;(2) Center for Cell Therapy and Tissue Repair, Charles University, 2nd Faculty of Medicine, 150 00 Prague 5, Czech Republic;(3) Faculty of Textile Engeneering, Technical University of Liberec, Hálkova 6, 461 17 Liberec, Czech Republic
Abstract:The goal was to electrospin 2-hydroxyethyl methacrylate — based biocompatible polymers and prepare submicron fibres (nanofibers) for biomedicinal applications. Syntheses of poly(2-hydroxyethyl methacrylate) (HEMA) and its copolymer with 2-ethoxyethyl methacrylate (EOEMA), and their characterization by viscometry and molecular weight are described. Their relation to electrospinning is discussed. Electrospinning of HEMA homopolymer from water-ethanol is successful for molecular weights 6.31 × 105 and 1.80 × 106 g/mol. Electrospinning of HEMA/EOEMA copolymers is feasible from ethanol. MediaObjects/11532_2007_Article_21_Fig1_HTML.jpg
Keywords:Nanofibers  electrospinning  2-hydroxyethyl methacrylate  2-ethoxyethyl methacrylate
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