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Total Synthesis of Three New Dihydrostilbenes from Bulbophllum odoratissimum
引用本文:Jin Guang LIN Wei Ge ZHANG Rui ZHAO Ze Yu NIU Kai BAO Dai Lin LIU Nai Li WANG Xin Shen YAO. Total Synthesis of Three New Dihydrostilbenes from Bulbophllum odoratissimum[J]. 中国化学快报, 2006, 17(3): 307-309
作者姓名:Jin Guang LIN Wei Ge ZHANG Rui ZHAO Ze Yu NIU Kai BAO Dai Lin LIU Nai Li WANG Xin Shen YAO
作者单位:Jin Guang LIN1,Wei Ge ZHANG1,2?,Rui ZHAO1,Ze Yu NIU1,Kai BAO1,Dai Lin LIU2,Nai Li WANG2,Xin Shen YAO2* 1School of Pharmaceutical Engineering,Shenyang Pharmaceutical University,Shenyang 110016 2The Research Center of Traditional Chinese Medicines and Natural Products,Research Institute of Tsinghua University,Shenzhen 518057
基金项目:We gratefully acknowledge Dr. Guo Liang CHEN, Shenyang Pharmaceutical University, for valuable discussion.
摘    要:
Natural stilbenoids are presently well known by their various kinds of bioactivity, such as antitumor, anti-inflammatory and platelet antiaggregation1. In our previous studies of naturally-occurring cytotoxic agents present in traditional Chinese medicine…

关 键 词:总合成 二氢基均二苯代乙烯 抗癌活性 天然化合物 中药 分离 提取 Bulbophllum odoratissimum
收稿时间:2005-07-20

Total Synthesis of Three New Dihydrostilbenes from Bulbophllum odoratissimum
Jin Guang LIN,Wei Ge ZHANG,Rui ZHAO,Ze Yu NIU,Kai BAO,Dai Lin LIU,Nai Li WANG,Xin Shen YAO. Total Synthesis of Three New Dihydrostilbenes from Bulbophllum odoratissimum[J]. Chinese Chemical Letters, 2006, 17(3): 307-309
Authors:Jin Guang LIN  Wei Ge ZHANG  Rui ZHAO  Ze Yu NIU  Kai BAO  Dai Lin LIU  Nai Li WANG  Xin Shen YAO
Abstract:
A total synthesis of three new dihydrostilbenes, 1, 2 and 3, which were isolated from Bulbophyllum odoratissimum Lindl. with significant cytotoxicity toward human cancer cell lines, was developed via Horner reaction etc. The natural products 1, 2 and 3 were obtained in 5.8%, 6.6% and 5.9%, respectively.
Keywords:Dihydrostilbene   total synthesis   Bulbophyllum odoratissimum Lindl.
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