当前状态数据下单变点危险率治愈模型的拟极大似然估计

变点危险率模型已受到广泛关注.它不仅可以更加直接地显示治疗效果或医学上的突破,也可以提供这些事件发生的时间点.在这篇文章中,我们提出当前状态数据下的单边点危险率治愈模型并探讨了这个模型的估计方法.我们建立了估计的大样本理论并通过模拟评估有限样本下的估计.

Pseudo-Maximum Likelihood Estimation in the Hazards Cure Model with a Single Change Point for Current Status Data

The change-point hazards model has received much attention, since it can not only display the impacts of treatments or medical breakthroughs more directly, but also provide the time point when those impacts occur. In this paper, we propose the single change-point hazards model for current status survival data with long-term survivors and investigate the estimation for the proposed model. Large-sample properties of the estimators are established. Simulation studies are carried out to evaluate the finite-sample performance of the estimation.