Verbenanone,an octahydro-5H-chromen-5-one from a Hawaiian-plant associated fungus FT431 |
| |
| Authors: | Chunshun Li Ariel M. Sarotti James Turkson Shugeng Cao |
| |
| Affiliation: | 1. Department of Pharmaceutical Sciences, Daniel K. Inouye College of Pharmacy, University of Hawaii at Hilo, 200 West Kawili Street, Hilo, HI 96720, United States;2. Cancer Biology, University of Hawaii Cancer Center, 701 Ilalo Street, Honolulu, HI 96813, United States;3. Instituto de Química Rosario (CONICET), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, Rosario 2000, Argentina |
| |
| Abstract: | ![]()
Verbenanone (1), a new secondary metabolite with a unique (4aS,8aS)-octahydro-5H-chromen-5-one moiety has been obtained from the endophytic fungus FT431, which was isolated from the native Hawaiian plant Verbena sp. The structure of compound 1 was characterized based on NMR and MS spectroscopic analysis. The absolute configuration (AC) of compound 1 was determined by Mosher acids. Compound 1 was tested against A2780 and A2780cisR, but it was inactive. |
| |
| Keywords: | Hawaii Endophytic fungi |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
