Regio et stereochimie de la reduction de derives d'alcools propargyliques catalysee par un complexe de palladium (O)

Regio and stereoselectivity of the palladium catalyzed reduction of propargylic halides and esters is greatly influenced by the nature of the hydride donor as by the leaving group. Best results in allene formation are observed in the reduction by lithium triethyl-borohydride of mesylates and phosphates. In the former case, reaction occurs with anti displacement of the sulfonyl group.