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Conversion of NGurethane protected arginine to ornithine in peptide solid phase synthesis |
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| Authors: | Hans Rink Peter Sieber Fritz Raschdorf |
| Institution: | Pharmaceuticals Division, CIBA-GEIGY Limited, CH 4002 Basel Germany |
| Abstract: | It is shown that Di-Adoc or Boc as guanidino protecting groups do not prevent the acylation and the subsequent conversion of arginine to ornithine in Fmoc solid phase peptide synthesis. |
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