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Preparation of chiral 5-deazaflavin derivatives and their asymmetric reduction of ethyl benzoylformate
Authors:Kiyoshi Tanaka  Tomoya Okada  Fumio Yoneda  Tomohisa Nagamatsu  Kazunori Kuroda
Institution:Faculty of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606, Japan;Faculty of Pharmaceutical Sciences, Kumamoto University, Oe-honmachi, Kumamoto 862, Japan
Abstract:1,5-Dihydro-5-deazaflavin derivatives possessing a chiral substituent at N(3) position were synthesized, with which moderate asymmetric induction was observed in the reduction of ethyl benzoylformate.
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