Preparation of chiral 5-deazaflavin derivatives and their asymmetric reduction of ethyl benzoylformate |
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Authors: | Kiyoshi Tanaka Tomoya Okada Fumio Yoneda Tomohisa Nagamatsu Kazunori Kuroda |
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Institution: | Faculty of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606, Japan;Faculty of Pharmaceutical Sciences, Kumamoto University, Oe-honmachi, Kumamoto 862, Japan |
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Abstract: | 1,5-Dihydro-5-deazaflavin derivatives possessing a chiral substituent at N(3) position were synthesized, with which moderate asymmetric induction was observed in the reduction of ethyl benzoylformate. |
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