The green and effective oxidation of alcohols to carboxylic acids with molecular oxygen via biocatalytic reaction |
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| Authors: | Jun-ichiro Hirano |
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| Affiliation: | Keio University, Department of Biosciences and Informatics 3-14-1 Hiyoshi, Yokohama 223-8522, Japan |
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| Abstract: | A clean and effective alcohol oxidizing system using three enzymes has been developed. Regeneration of NAD+ by NADH oxidase with molecular oxygen enabled to oxidize alcohols to carboxylic acids in good yield under mild conditions (25 °C, 1 atm). |
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| Keywords: | Alcohol oxidation Molecular oxygen Biocatalyst Green chemistry Regeneration of cofactor |
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