Synthesis in the diazasteroid group. XII Syntheses of the 10,17-diazasteroid and 10-aza-17-thiasteroid systems

Upon desulfurization with Raney Ni, the condensed heterocycles 2a,b prepared by cyclization from β-ketosulfoxides 1a,b gave β-ketones 3a,b , which were condensed with 2-carbethoxymethyl-piperidine 4 to afford the 10,17-diazasteroid 6 and the 10-aza-17-thiasteroid 7 , respectively.