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An efficient and simple method for synthesis of 2,2-disubstituted-2H-chromenes by condensation of a phenol with a 1,1-disubstituted propargyl alcohol using BF3·Et2O as the catalyst
Authors:Sridhar Madabhushi  Raveendra JillellaKondal Reddy Godala  Kishore Kumar Reddy MalluChina Ramanaiah Beeram  Narsaiah Chinthala
Affiliation:Fluoroorganics Division, Indian Institute of Chemical Technology, Hyderabad 500607, India
Abstract:An efficient and simple method for the synthesis of 2,2-disubstituted-2H-chromenes by one-step cyclocondensation of a phenol with a variety of 1,1-disubstituted propargyl alcohols using BF3·Et2O as the catalyst is described.
Keywords:2,2-Disubstituted-2H-chromenes   Phenol   Cyclocondensation   1,1-Disubstituted propargyl alcohol   BF3·  Et2O   Lewis acid catalysis
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