Effect of gamma radiation on dilute aqueous solutions and thin films of N-succinyl chitosan |
| |
Authors: | Chutima Vanichvattanadecha Pitt Supaphol Naotsugu Nagasawa Seiichi Tokura Hiroshi Tamura |
| |
Institution: | a The Petroleum and Petrochemical College, Chulalongkorn University, Pathumwan, Bangkok 10330, Thailand b The Center for Petroleum, Petrochemicals and Advanced Materials, Chulalongkorn University, Pathumwan, Bangkok 10330, Thailand c Takasaki Radiation Chemistry Research Establishment, Japan Atomic Energy Research Institute,1233 Watanuki-machi, Takasaki, Gunma 370-1292, Japan d Faculty of Chemistry, Materials and Bioengineering, and HRC, Kansai University, Suit-shi, Osaka 564-8680, Japan |
| |
Abstract: | N-Succinyl chitosan (N-SC) products with various degrees of substitution were synthesized by a direct reaction between chitosan and succinic anhydride. The susceptibility of the as-synthesized polymers to degradation upon their exposure to γ-ray radiation was investigated. The results were compared with the as-received chitosan. The size exclusion chromatographic results showed that chitosan and N-SC products in their dilute aqueous solution state were more subservient to degradation by γ-ray radiation than in their solid film state, despite the much less exposure to the radiation (i.e., 5-30 kGy for the solutions versus 20-100 kGy for the films). Increasing the radiation dose resulted in the rather monotonous decrease in the molecular weights of the polymers. Structural analyses of the irradiated polymers by Fourier-transformed infrared spectroscopy (FT-IR) and UV-visible spectrophotometry indicated the increase in the amount of carbonyl groups with the radiation dose. The formation of the carbonyl groups suggested that the radiolysis of chitosan and N-SC products occurred at the glycosidic linkages. In addition, FT-IR, elemental analysis and proton nuclear magnetic resonance spectroscopy (1H NMR) results suggested that γ-ray radiation affected both the N-acetyl and N-substituted groups on the polymer chains. |
| |
Keywords: | Chitosan Substituted chitosan N-Succinyl chitosan Degradation Radiolysis Gamma radiation |
本文献已被 ScienceDirect 等数据库收录! |
|