Two New Daphniphyllum Alkaloids from Daphniphyllum calycinum |
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| Authors: | Du‐Qiang Luo Wen‐Liang Zhu Xiao‐Long Yang Shu‐Juan Liang Zhi‐Ran Cao |
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| Affiliation: | 1. College of Life Science, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Hebei University, Baoding 071002, P.?R. China;2. College of Pharmaceutical Science, Hebei University, Baoding 071002, P.?R. China;3. Health Science Center, Hebei University, Baoding 071002, P.?R. China |
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| Abstract: | Two new daphniphyllum alkaloids named 2‐hydroxyyunnandaphnine D ( 1 ) and methyl 7‐hydroxyhomodaphniphyllate ( 2 ), together with eight known alkaloids, daphnioldhanin D, calyciphylline F, calyciphylline B, deoxycalyciphylline B, daphnicyclidin H, macropodumine C, 9,10‐epoxycalycine A, and yunnandaphnine A, were isolated from the stems and leaves of Daphniphyllum calycinum. Their structures and relative configurations were established on the basis of spectral evidence (including 2D‐NMR) and subsequently confirmed by a single‐crystal X‐ray crystallographic diffraction analysis. |
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| Keywords: | Daphniphyllum calycinum Daphniphyllum alkaloids Alkaloids Yunnandaphnine D, 2‐hydroxy‐ Methyl 7‐hydroxyhomodaphniphyllate X‐Ray crystallography |
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