Two New Disulfated Triterpenoids from Zygophyllum fabago |
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| Authors: | Saleha S. Khan Afsar Khan Amir Ahmed Viqar U. Ahmad Umar Farooq Saima Arshad Sadia Bader Aqib Zahoor Imran N. Siddiqui Bilge Sener Nurgun Erdemoglu |
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| Affiliation: | 1. H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi‐75270, Pakistan (phone: +92‐21‐34819020;2. fax: +92‐21‐34819018‐9);3. Department of Chemistry, COMSATS Institute of Information Technology, Abbottabad‐22060, Pakistan;4. Pharmaceutical Division, Pakistan Council of Scientific and Industrial Research Laboratories Complex, Karachi 75280, Pakistan;5. Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara‐06330, Turkey |
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| Abstract: | ![]()
From the aerial parts of Zygophyllum fabago, two new monosodium salts of sulfated derivatives of ursolic acid, along with two known quinovic acid glycosides were isolated. The structures of the new compounds were determined as (3β,4α)‐3,23,30‐trihydroxyurs‐20‐en‐28‐al 3,23‐di(sulfate) sodium salt (1 : 1) ( 1 ) and of (3β,4α)‐3,23,28‐trihydroxyurs‐20‐en‐30‐yl β‐D ‐glucopyranoside 3,23‐di(sulfate) sodium salt (1 : 1) ( 2 ) with the molecular formula C30H47NaO10S2 and C36H59NaO15S2, respectively. The structures of the known compounds were 3‐O‐(2‐O‐sulfo‐β‐D ‐quinovopyranosyl)quinovic acid 28‐β‐D ‐glucopyranosyl ester ( 3 ) and 3‐O‐(β‐D ‐glucopyranosyl)quinovic acid 28‐β‐D ‐glucopyranosyl ester ( 4 ) (quinovic acid=(3β)‐3‐hydroxyurs‐12‐ene‐27,28‐dioic acid). The structures of all these compounds were determined by using 1D‐ and 2D‐NMR spectroscopic techniques. |
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| Keywords: | Zygophyllum fabago Ursolic acids Glycosides |
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