Two New Lycopodine Alkaloids from Huperzia serrata |
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| Authors: | Jinhe Jiang Ying Liu Kang Min Bi Jing Liqin Wang Yan Zhang Yegao Chen |
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| Institution: | 1. Department of Chemistry, Yunnan Normal University, Street 121, Kunming 650092, P.?R. China, (phone and fax: +86‐871‐5516061);2. Diqing Institute of Agricultural Science, Shangrila 674400, P.?R. China;3. Department of Chemistry, Kunming Medical College, West Reming Road, Kunming 650092, P.?R. China |
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| Abstract: | Two new lycopodine alkaloids, (12β)‐12‐hydroxyhuperzine G ( 1 ) and (5β,6β,15α)‐15‐methyllycopodane‐5,6‐diol ( 2 ), were isolated from the whole plants of Huperzia serrata, together with six known compounds, huperzines A, B, and G, phlegmariurine B, (8β)‐8‐hydroxyphlegmariurine B, and lycoposerramine D. Their structures were elucidated on the basis of spectroscopic analysis, including HR‐ESI‐MS, 1H‐ and 13C‐NMR, DEPT, 1H,1H‐COSY, HSQC, HMBC, and NOESY data. |
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| Keywords: | Huperzia serrata Lycopodine alkaloids Alkaloids Huperzine G (12β )‐12‐hydroxy‐ Lycopodane‐5 6‐diol (5β 6β 15α )‐15‐methyl‐ |
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