Synthesis of 3-aminomethyl-substituted pyrazoles and isoxazoles |
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Authors: | D M Musatov E V Starodubtseva A K Rakishev O V Turova M G Vinogradov |
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Institution: | 1.Zelinskii Institute of Organic Chemistry,Russian Academy of Sciences,Moscow,Russia |
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Abstract: | A series of new 3-(aminomethyl)pyrazoles and 3-(aminomethyl)isoxazoles was synthesized along a route involving the formation
as key intermediates of esters of 5-substituted 1H-pyrazole-3-carboxylic and 1H-isoxazole-3-carboxylic acids. All compounds obtained were characterized by physicochemical constants, IR, 1H, 13C NMR, and mass spectra. |
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