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盐酸托哌酮的NMR研究
引用本文:黄建设,吴军,肖志会,张偲. 盐酸托哌酮的NMR研究[J]. 波谱学杂志, 2005, 22(2): 133-139
作者姓名:黄建设  吴军  肖志会  张偲
作者单位:中国科学院 南海海洋研究所, 广东省海洋药物重点实验室,广东 广州 510301
基金项目:grant from the open program of Guangdong Key Laboratory of Marine Materia Medica,,
摘    要:应用1D NMR和脉冲梯度场2D NMR技术深入研究盐酸托哌酮的溶液结构,对其1H和13C NMR化学位移进行全归属,并讨论其立体化学.

关 键 词:归属   二维核磁共振   盐酸托哌酮   立体化学  

Structure Elucidation of Tolperisone Hydrochloride by NMR
Huang Jian-she,WU Jun,XIAO Zhi-hui,ZHANG Si. Structure Elucidation of Tolperisone Hydrochloride by NMR[J]. Chinese Journal of Magnetic Resonance, 2005, 22(2): 133-139
Authors:Huang Jian-she  WU Jun  XIAO Zhi-hui  ZHANG Si
Affiliation:Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of  Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China
Abstract:The structure of tolperisone hydrochloride was elucidated by 1D and 2D NMR techniques (i.e., gCOSY, gNOESY, gHSQC and gHMBC). The {}+1H and {}+{13}C chemical shifts of this compound were completely assigned, and its stereochemistry was investigated by NOESY.
Keywords:NMR  chemical shift  2D NMR  tolperisone hydrochloride  stereochemistry
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