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Regiocontrolled [3+2] quinone-nitrile oxide entry to type II polyketide building blocks
Authors:Joel L StevensThomas D Welton  Jay P DevilleVictor Behar
Institution:Department of Chemistry, Rice University MS 60, Houston, TX 77251, USA
Abstract:Bromine substituents on naphthoquinones effectively activate and orient the 3+2] dipolar cycloaddition reaction with nitrile oxides to generate regiodefined type II polyketide building blocks.
Keywords:
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