Advances in digital holographic micro-PTV for analyzing microscale flows |
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Authors: | Yong-Seok Choi Kyung-Won Seo Myong-Hwan Sohn Sang-Joon Lee |
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Affiliation: | a Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), Pohang 790-784, Republic of Korea b Center for Biofluid and Biomimic Research, Pohang University of Science and Technology (POSTECH), Pohang 790-784, Republic of Korea c WCU Program Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology (POSTECH), Pohang 790-784, Republic of Korea |
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Abstract: | The accurate three-dimensional (3D) velocity field measurement technique has been receiving large attention in the study of microfluidics. DHM-PTV technique was developed by combining the digital holographic microscopy and particle tracking velocimetry technique. DHM-PTV is an ideal method for measuring three-component-three-dimensional (3C-3D) velocity field in a microscale flow with a fairly good spatial resolution. The advances in the DHM-PTV technique enable the measurement of various microscale flows, such as transport of red blood cells in a microtube and 3D flows in microfluidic devices. DHM-PTV is also applied in studying the motile behavior of swimming microorganisms. DHM-PTV would play an important role in ascertaining the undiscovered basic physics in various microscale and biofluid flow phenomena. In the current study, the basic principle of the DHM-PTV technique and its typical applications to microscale flows are introduced and discussed. |
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Keywords: | Digital holographic microscopy Three-dimensional particle tracking velocimetry (3D PTV) Microscale flows Biofluid flows |
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