Efficient synthesis of isoflavone analogues via a Suzuki coupling reaction |
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Authors: | Ke Ding |
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Institution: | Departments of Internal Medicine and Medicinal Chemistry, University of Michigan Comprehensive Cancer Center, University of Michigan, 1500 East Medical Center Dr., Ann Arbor, MI 48109-0934, USA |
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Abstract: | Analogues of 3-aryl-8-isobutyl-5,6,7-trihydroxy-2-methyl-4H-chromen-4-one were synthesized with high yields via the Suzuki coupling reaction of 3-iodo-8-isobutyl-5,6,7-trimethoxy-2-methyl-4H-chromen-4-one with different aryl boronic acids. |
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Keywords: | Isoflavone Synthesis Suzuki coupling reaction |
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