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A carbohydrate-based approach for the total synthesis of strictifolione
Authors:CV Ramana  N Raghupathi  Mukund S Chorghade
Institution:a National Chemical Laboratory, Dr. Homi Bhabha Road, Pune 411 008, India
b Chorghade Enterprise, 14, Carlson Circle, Natick, MA 01760, USA
Abstract:A chiral pool approach starting with d-glucose, using the Yamaguchi protocol and a Z-selective HWE reaction followed by lactonization, has been applied to execute the total synthesis of strictifolione.
Keywords:Strictifolione  d-Glucose" target="_blank">d-Glucose  Double elimination  Horner-Wadsworth-Emmons reaction  Yamaguchi protocol  Lactonization
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