Recent advances on copper-catalyzed asymmetric synthesis and their potential biological applications |
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| Affiliation: | 1. Borneo Research on Algesia Inflammation and Neurodegeneration (BRAIN) Group, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Jalan UMS, Kota Kinabalu 88400, Sabah, Malaysia;2. Department of Chemistry, Government College University Faisalabad, 38000, Pakistan;3. School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China;4. Faculty of Pharmacy, Universiti Teknologi MARA Cawangan Selangor Kampus Puncak Alam, Bandar Puncak Alam 42300, Selangor D. E., Malaysia;5. Atta-ur-Rahman Institute for Natural Product Discovery (AuRIns), Universiti Teknologi MARA Cawangan Selangor Kampus Puncak Alam, Bandar Puncak Alam 42300, Selangor D. E., Malaysia |
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| Abstract: | 
An asymmetric catalysis is a form of catalytic reaction wherein a chiral catalyst controls the production of a chiral molecule to favour the synthesis of one stereoisomer over another. It's a good way to make stereoisomeric molecules for pharmacological purposes. Among the transition metals, copper is a cost-effective, plentiful, and less poisonous metal. This review focused on the asymmetric transformations in the last fifteen years. |
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| Keywords: | Copper Asymmetric Catalysis Stereoisomers Enantioselective |
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