Neue β-Lactam-Antibiotika. Über die Darstellung und Decarbonylierung von 3-Formylcephem-Verbindungen. Modifikationen von Antibiotica, 12. Mitteilung [1]

Benzhydrylic esters of 3-unsubstituted cephem-4-carboxylic acids of types 9 and 10 (Scheme 2) are prepared by decarbonylation of esters of 3-formylcephem compounds of type 2 with tris-triphenylphosphine-rhodium chloride. The preparation of the starting materials 2 and 5 , as well as of the nucleus 13 is described.