Cyanoethylation of some n-substituted 2,5-dimethyl-4-piperidones

1,2,5-Trimetnyl- and 1-(-chlorocrotyl)-2,5-dimethyl-5-(-cyanoethyl)-4-piperidones were synthesized and separated into individual isomers. The corresponding isomeric 5-(-carboxyethyl)-4-piperidones were obtained by hydrolysis. The isomeric 1,2,5-trimethyl-3,5-bis(-cyanoethyl)- and 1,2,5-trimethyl-3,3,5-tris(-cyanoethyl)-4-piperidones were synthesized by subsequent cyanoethylation of the individual 1,2,5-trimethyl-5-(-cyanoethyl)-4-piperidone isomers.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 479–481, April, 1971.