苯基脲类除草剂分子印迹聚合物的合成和识别性能研究

以N-(4-异丙基苯基)-N′-亚丁基脲为模板, 甲基丙烯酸为功能单体, 乙二醇二甲基丙烯酸酯为交联剂制备了分子印迹聚合物(MIP). 研究了MIP对苯基脲类除草剂的亲和性和选择性. 在二氯甲烷流动相中制备的MIP对异丙隆(IP)、 非草隆(FN)、 甲氧隆(MX)、 敌草隆(DU)、 绿麦隆(CT)、 枯莠隆(DF)、 灭草隆(MN)、 草不隆(NB)、 播土隆(BT)和伏草隆(FU)等除草剂呈现出较高的亲和性, 而非印迹聚合物(NIP)对文中所用的14种苯基脲类除草剂均表现出非常低的保留或几乎没有保留. 实验及Mulliken电荷计算的结果显示， 苯基脲除草剂分子中的N′原子是主要的识别位点.

Preparation of Molecularly Imprinted Polymer and Its Recognition Property for Phenylurea Herbicides

A molecularly imprinted polymer(MIP) was prepared with N-(4-isopropylphenyl) -N′-butyleneurea as a template and MAA as a functional monomer and EDMA as a cross-linker. The affinities and selectivities of the MIP for phenylurea herbicides were studied. Among the fourteen phenylurea herbicides tested, the MIP prepared shows obviously high affinities and selectivities for ten chemicals(monuron, diuron, isoproturon, fenuron, chlortoluron, difenoxuron, metoxuron, neburon, buturon and fluometuron) with dichloromethane as the mobile phase while the non-imprinted polymer shows very low affinities for all the phenylurea herbicides tested. Recognition mechanism was also discussed. The results of the experiments and Mulliken atomic charges calculated indicate that the recognition site is mainly located at the N′ position of phenylurea herbicides.