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Biopolymer-based nanoparticles and microparticles: Fabrication,characterization, and application
Institution:1. Department of Food Science, University of Massachusetts, Amherst, MA, USA;2. Department of Microbial and Molecular Systems, KU Leuven, Leuven, Belgium;3. Department of Biochemistry, Faculty of Science, King Abdulaziz University, P. O. Box 80203 Jeddah 21589, Saudi Arabia;1. CEB - Centre of Biological Engineering, University of Minho, Braga, Portugal;2. Instituto de Biologia Experimental e Tecnológica, Avenida da República, Quinta-do-Marquês, Estação Agronómica Nacional, Apartado 12, 2781-901 Oeiras, Portugal;3. LEPABE - Laboratório de Engenharia de Processos, Ambiente, Biotecnologia e Energia, University of Porto, Porto, Portugal;1. Top Institute Food & Nutrition, P.O. Box 557, 6700 AN Wageningen, The Netherlands;2. Laboratory of Physics and Physical Chemistry of Foods, Wageningen University, P.O. Box 17, 6700 AA Wageningen, The Netherlands;3. Laboratory of Physical Chemistry and Colloid Science, Wageningen University, P.O. Box 8038, 6700 EK Wageningen, The Netherlands;4. Department of Biomedical Engineering, University Medical Center Groningen, University of Groningen, P.O. Box 196, 9700 AD Groningen, The Netherlands
Abstract:Tailor-made microparticles and nanoparticles are finding increasing use in food products to alter their nutritional characteristics, flavor profile, appearance, rheology, stability, and processability. These particles are often fabricated from food-grade biopolymers, such as proteins and polysaccharides. Food biopolymers display a diverse range of molecular and physicochemical properties (e.g. molecular weight, charge, branching, flexibility, polarity, and solubility) which enables the assembly of colloidal particles that exhibit a broad range of functional attributes. By careful selection of appropriate biopolymers and assembly methods, biopolymer particles can be fabricated with tailored behaviors or features. In this article, we review recent developments in the design and fabrication of functional biopolymer nanoparticles and microparticles, and highlight some of the challenges that will be the focus of future research.
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