Synthesis of fluorinated 1,8-naphthyridinone derivatives |
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Authors: | Joseph T Repine Douglas S Johnson Timothy Stuk Michael A Stier Zhixiang Yang |
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Institution: | a Pfizer Global Research and Development, 2800 Plymouth Road, Ann Arbor, Michigan 48105, USA b Naeja Pharmaceuticals, 4290-91a Street, Edmonton, Alberta, Canada T6E 5V2 |
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Abstract: | Processes for the synthesis of fluorinated 1,8-naphthyridinone derivatives including 6,7-difluoro-1,8-naphthyridin-2-one are described. |
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