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Ultrasound promoted synthesis of some novel fused pyrans
Authors:Saleh Tamer S  Abd El-Rahman Naglaa M  Elkateb Ahmed A  Shaker Nehal O  Mahmoud Naema A  Gabal Shimaa A
Affiliation:a Green Chemistry Department, National Research Centre, Dokki, Cairo 12622, Egypt
b Chemistry Department, Faculty of Science, King AbdulAziz University, Jeddah 21589, Saudi Arabia
c Chemistry Department, Faculty of Science (Girls’ Branch), Al-Azhar University, Nasr City, Cairo 11754, Egypt
Abstract:
Novel fused pyrans were synthesized from the reaction of the tetrahydropyran-4-one with arylidine malononitriles. Different fused pyran derivatives were obtained from the mentioned reaction depending on type of catalyst used and type of energy used. Reactions were carried out under silent and ultrasonic conditions. In general, it was found that sometimes ultrasound irradiations change the reaction path in comparing with silent condition. In addition to improvement in reaction times, the products were obtained in high yields and their structures were determined by elemental analyses, spectral data.
Keywords:Tetrahydropyran-4-one   Isochromene   Tetrahydropyrano[4,3-b]pyran   Pyrano[4,3-b]pyridine   Ultrasound irradiation
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