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Synthesis and characterization of well‐defined lactic acid–PEG cooligomers and its tricarbonyl rhenium conjugates
Authors:Hua Zhu  Xiaoping Xu  Wei Cui  Yuanqing Zhang  Huaping Mo  Yu‐Mei Shen
Institution:1. Shanghai Center for Systems Biomedicine, Ministry of Education Key Laboratory of Systems Biomedicine, Shanghai Jiao Tong University, Shanghai 200240, China;2. Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China;3. Shanghai Institute of organic chemistry, Chinese Academy of Sciences, Shanghai 200032, China
Abstract:This article describes the synthesis and characterization of hydroxyl tailored, molecularly defined biodegradable cooligomers capable of chelating rhenium for potential radiopharmaceuticals. New insights were gained during the synthesis of lactide based on dimethylaminopyridine‐catalyzed transesterification. © 2011 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2011
Keywords:cooligomer  lactic acid  polyethylene glycol (PEG)  rhenium  transesterification
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